Epigenetics and lifestyle
نویسندگان
چکیده
منابع مشابه
Environmental Epigenetics: Crossroad between Public Health, Lifestyle, and Cancer Prevention
Epigenetics provides the key to transform the genetic information into phenotype and because of its reversibility it is considered an ideal target for therapeutic interventions. This paper reviews the basic mechanisms of epigenetic control: DNA methylation, histone modifications, chromatin remodeling, and ncRNA expression and their role in disease development. We describe also the influence of ...
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Differentiation is an epigenetic process which is installed by changes of transcriptional programs over successive cellular divisions. A number of studies have reported the effects of biochemical modifications of chromatin (DNA and chromatin proteins) on the regulation of transcription. Although, these studies are able to explain how transcription of a given gene is regulated (toward activation...
متن کاملEpigenetics
By the time the reader reaches Chapter 20, which focuses specifically on cancer, the mechanisms and symptoms of cancer are relatively easy to understand. Chapter 20 covers topics such as the cellular phenotypes of cancer, genes linked to cancer, and cancer treatment. While the primary literature citations at the end of the chapter will provide good starting points for the curious student, a mor...
متن کاملEpigenetics
In this issue we focus on the topic of Epigenetics, the study of heritable phenotypic traits not encoded by the genetic sequence. While every cell in your body has a copy of your genetic code in the form of DNA, many of the unique features between different cell types and between different individuals arise from unique patterns of gene expression. In recent decades, it has become increasingly c...
متن کاملHIGHLIGHTED TOPIC Epigenetics in Health and Disease Epigenetics and cancer
Kanwal R, Gupta S. Epigenetics and cancer. J Appl Physiol 109: 598–605, 2010. First published March 4, 2010; doi:10.1152/japplphysiol.00066.2010.— Epigenetic modifications are central to many human diseases, including cancer. Traditionally, cancer has been viewed as a genetic disease, and it is now becoming apparent that the onset of cancer is preceded by epigenetic abnormalities. Investigators...
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ژورنال
عنوان ژورنال: Epigenomics
سال: 2011
ISSN: 1750-1911,1750-192X
DOI: 10.2217/epi.11.22